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 Formulary Chapter 4: Central nervous system - Full Chapter
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04.03.01  Expand sub section  Tricyclic and related antidepressant drugs
04.03.01  Expand sub section  Tricyclic antidepressants
Amitriptyline
(Antidepressant)
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Formulary
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NOTE: There is more than one monograph for this medicine, click here to search for formulary status and its use for other indications. 

Provider notes

  • NMUH:
    • No restriction stated
  • RFL:
    • No restriction stated
  • RNOH:
    • Oral solution available as 25 mg/5mL
  • UCLH:
  • WH:
    • No restriction stated
  • CIFT:
    • Approved for depression
  • BEHMT:
    • Approved for depression
 
Clomipramine (Antidepressant)
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Formulary
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Provider notes

  • NMUH:
    • No restriction stated
  • RFL:
    • No restriction stated
  • RNOH:
    • Non-formulary
  • UCLH:
  • WH:
    • No restriction stated
  • CIFT:
    • Approved for depression 
  • BEHMT:
    • Approved for depression 
 
Dosulepin
(Antidepressants)
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Formulary
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NOTE: There is more than one monograph for this medicine, click here to search for formulary status and its use for other indications. 

Not approved for any indication in line with NHS England 'Items which should not routinely be prescribed in primary care' guidance (JFC January 2020)

Provider notes

  • NMUH:
    • For continuation ONLY
    • Non-formulary for initiation in all indications
  • RFL:
    • No restriction stated
  • RNOH:
    • Non-formulary
  • UCLH:
  • WH:
    • No restriction stated
  • CIFT:
    • Non-formulary
  • BEHMT:
    • Non-formulary
 
Imipramine
(Antidepressant)
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Formulary
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NOTE: There is more than one monograph for this medicine, click here to search for formulary status and its use for other indications. 

Provider notes

  • NMUH:
    • No restriction stated
  • RFL:
    • No restriction stated
  • RNOH:
    • Non-formulary
  • UCLH:
  • WH:
    • No restriction stated
  • CIFT:
    • Approved for depression
  • BEHMT:
    • Approved for depression
 
Lofepramine
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Formulary
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Provider notes

  • NMUH:
    • No restriction stated
  • RFL:
    • No restriction stated
  • RNOH:
    • Non-formulary
  • UCLH:
  • WH:
    • No restriction stated
  • CIFT:
    • Approved for depression 
  • BEHMT:
    • Approved for depression 
 
Nortriptyline
(Antidepressant)
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Restricted Drug Restricted
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NOTE: There is more than one monograph for this medicine, click here to search for formulary status and its use for other indications. 

Provider notes

  • NMUH:
    • For continuation ONLY
  • RFL:
    • Restricted for initiation until after a discussion with liaison psychiatry team
  • RNOH:
    • Non-formulary
  • UCLH:
  • WH:
    • Non-formulary
  • CIFT:
    • Non-formulary
  • BEHMT:
    • Non-formulary
 
Trimipramine
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Formulary
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Provider notes

  • NMUH:
    • No restriction stated
  • RFL:
    • No restriction stated
  • RNOH:
    • Non-formulary
  • UCLH:
    • Symptoms of depressive illness especially if sedation required
  • WH:
    • 25mg tablets and 50mg capsules only
  • BEHMT:
    • Non-formulary
  • CIFT:
    • Non-formulary
 
04.03.01  Expand sub section  Related antidepressants
 ....
 Non Formulary Items
Amitriptyline + Perphenazine
(Triptafen)

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Non Formulary
Doxepin

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Non Formulary
  
Key
note Notes
Section Title Section Title (top level)
Section Title Section Title (sub level)
First Choice Item First Choice item
Non Formulary Item Non Formulary section
Restricted Drug
Restricted Drug
Unlicensed Drug
Unlicensed
Track Changes
Display tracking information
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Link to adult BNF
click to search medicines.org.uk
Link to children's BNF
click to search medicines.org.uk
Link to SPCs
Homecare
Homecare

Traffic Light Status Information

Status Description

GP - Amber

Medicines that should be initiated by a specialist. Prescribing can be transferred to primary care once the patient has been stabilised.

Shared care: For drugs with regular, ongoing need for monitoring and/or assessment of efficacy or toxicity. Prior agreement must be obtained by the specialist from the primary care provider before prescribing responsibility is transferred. The shared care protocol must have been agreed by the relevant secondary care trust Drugs and Therapeutics Committee(s) (DTC) and approved by the North Central London JFC.

Fact sheet: For drugs with some concerns surrounding safety or efficacy but do not require regular monitoring and/or monitoring of effectiveness/toxicity.

  

GP - Red

Medicines which should normally be prescribed by specialists only (hospital only).

For patients already receiving prescriptions in primary care - continue. No new patients to receive prescriptions in primary care.

See link for the complete NCL Red List https://www.ncl-mon.nhs.uk/wp-content/uploads/2017/08/ncl_red_list.pdf

  

Black

Medicines not recommended for routine use in primary or secondary care.

Medicines, which the North Central London JFC has actively reviewed and does not recommend for use at present due to limited clinical and/or cost effective data.

  

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