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Joint Formulary
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 Formulary Chapter 4: Central nervous system - Full Chapter
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04.01.02  Expand sub section  Anxiolytics
04.01.02  Expand sub section  Benzodiazepines
Chlordiazepoxide
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Restricted Drug Restricted
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Provider notes

  • NMUH:
    • No restriction stated
  • RFL:
    • Restricted to in-patient use for alcohol detoxification and anxiety.
  • RNOH:
    • No restriction stated
  • UCLH:
  • WH:
    • No restriction stated
  • CIFT:
    • Approved for
      • Anxiolytic
      • Alcohol withdrawal
      • Acute phase of mania (off-label)
  • BEHMT:
    • Approved for  
      • Anxiolytic
      • Alcohol withdrawal
 
Diazepam
(Anxiolytic)
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Formulary
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NOTE: There is more than one monograph for this medicine, click here to search for formulary status and its use for other indications. 

Provider notes

  • NMUH:
    • No restriction stated
  • RFL:
    • No restriction stated
  • RNOH:
    • Stored and supplied as a controlled drug on ITU, CHDU, Philip Newman ward and Ian Munroe ward
    • Oral solution available as 2 mg/5mL
  • UCLH:
  • WH:
    • Tablets 2 mg, 5 mg, 10 mg.
    • Oral solution 2 mg/5 ml, 5mg/5 ml 
    • Injection (emulsion) 10 mg/2 ml - Diazemuls
  • CIFT:
    • Approved for
      • Anxiolytic
      • Alcohol withdrawal
      • Acute phase of mania (off-label)
      • Benzodiazepine dependence (off-label)
  • BEHMT:
    • Approved for
      • Anxiolytic
      • Alcohol withdrawal
      • Acute phase of mania (off-label)
      • Benzodiazepine dependence (off-label)
 
Lorazepam
(Hypnotic)
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Formulary
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NOTE: There is more than one monograph for this medicine, click here to search for formulary status and its use for other indications. 

 Provider notes

  • NMUH:
    • No restriction stated
  • RFL:
    • No restriction stated
  • RNOH:
    • The injection (4 mg in 1mL) must be stored in a refrigerator
  • UCLH:
  • WH:
    • No restriction stated
  • CIFT:
    • Approved for
      • Anxiolytic
      • Rapid tranquillisation
      • Acute phase of mania and aggression (off-label)
      • Alcohol detoxification (off-label)
  • BEHMT:
    • Approved for 
      • Anxiolytic
      • Rapid tranquillisation
 
Oxazepam
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Formulary
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Approved for management of acute alcohol withdrawal in patients with severe liver disease where chlordiazepoxide is not appropriate (JFC September 2019).

Provider notes

  • NMUH:
    • As per indication above
  • RFL:
    • Non-formulary
  • RNOH:
    • Non-formulary
  • UCLH:
  • WH:
    • As above
  • CIFT:
    • Approved as
      • Anxiolytic
      • Alcohol detoxification (off-label)
  • BEHMT approvals:
    • Non-formulary
 
04.01.02  Expand sub section  Buspirone
04.01.02  Expand sub section  Beta blockers
04.01.02  Expand sub section  Meprobamate to top
 ....
 Non Formulary Items
Alprazolam

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Non Formulary
  
Key
note Notes
Section Title Section Title (top level)
Section Title Section Title (sub level)
First Choice Item First Choice item
Non Formulary Item Non Formulary section
Restricted Drug
Restricted Drug
Unlicensed Drug
Unlicensed
Track Changes
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Homecare
Homecare

Traffic Light Status Information

Status Description

GP - Amber

Medicines that should be initiated by a specialist. Prescribing can be transferred to primary care once the patient has been stabilised.  

Shared care: For drugs with regular, ongoing need for monitoring and/or assessment of efficacy or toxicity. Prior agreement must be obtained by the specialist from the primary care provider before prescribing responsibility is transferred. The shared care protocol must have been agreed by the relevant secondary care trust Drugs and Therapeutics Committee(s) (DTC) and approved by the North Central London JFC.

Fact sheet: For drugs with some concerns surrounding safety or efficacy but do not require regular monitoring and/or monitoring of effectiveness/toxicity.

  

GP - Red

Medicines which should normally be prescribed by specialists only (hospital only).

For patients already receiving prescriptions in primary care - continue. No new patients to receive prescriptions in primary care.

See link for the complete NCL Red List https://www.ncl-mon.nhs.uk/wp-content/uploads/2017/08/ncl_red_list.pdf

  

Black

Medicines not recommended for routine use in primary or secondary care.

Medicines, which the North Central London JFC has actively reviewed and does not recommend for use at present due to limited clinical and/or cost effective data.

  

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