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 Formulary Chapter 2: Cardiovascular system - Full Chapter
02.11  Expand sub section  Antifibrinolytic drugs and haemostatics
02.11  Expand sub section  Blood-related products
Antithrombin III
(Kybemin)
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Restricted Drug Restricted
High Cost Medicine
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Provider notes

  • NMUH:
    • Non-formulary
  • RFL:
    • Available through the haemophilia centre
  • RNOH:
    • Non-formulary
  • UCLH:
  • WH:
    • Non-formulary
 
Factor IX
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Restricted Drug Restricted
High Cost Medicine
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Provider notes

  • NMUH:
    • Non-formulary
  • RFL:
    • Available from the haemophilia centre
    • Alphanine®, Alprolix® (eftrenonacog alfa), Benefix® (nonacog alfa), Idelvion® (albutrepenonacog alfa), Refixia® (nonacog beta pegol)
  • RNOH:
    • Non-formulary
  • UCLH:
  • WH:
    • Non-formulary
 
Factor VIIa, recombinant
(Novo 7)
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Restricted Drug Restricted
High Cost Medicine
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Provider notes

  • NMUH:
    • Non-formulary
  • RFL:
    • Available from the haemophilia centre
  • RNOH:
    • No restriction stated
  • UCLH:
  • WH:
    • Non-formulary
 
Factor VIII
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Restricted Drug Restricted
High Cost Medicine
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Provider notes

  • NMUH:
    • PbR (Payment by Results) excluded drug
  • RFL:
    • Available from the Haemophilia centre
    • Advate® (octocog alfa), Elocta® (efmoroctocog alfa), Fanhdi®, Fibrogammin®, Helixate Nexgen® (octocog alfa), Kogenate® (octocog alfa), Novoeight®, Optivate®, Refacto AF® (moroctocog alfa)
  • RNOH:
    • Non-formulary
  • UCLH:
  • WH:
    • Non-formulary
 
Factor VIII + von Willebrand factor
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Restricted Drug Restricted
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Provider notes

  • NMUH:
    • Non-formulary
  • RFL:
    • Available through the haemophilia centre
    • Voncento®, Wilate®, Haemate P®
  • RNOH:
    • Non-formulary
  • UCLH:
  • WH:
    • Non-formulary
 
Factor VIII Inhibitor Bypassing Fraction
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High Cost Medicine
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Provider notes

  • NMUH:
    • Non-formulary
  • RFL:
    • Available through the haemophilia centre
    • Feiba®
  • RNOH:
    • Non-formulary
  • UCLH:
  • WH:
    • Non-formulary
 
Factor VIII, recombinant
(Susoctocog alfa; Obizur)
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Restricted Drug Restricted
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Provider notes

  • NMUH:
    • Non-formulary
  • RFL:
    • Approved for acquired haemophilia A in line with NHSE clinical commissioning policy 170061P (RFL only; JFC November 2018)
  • RNOH:
    • Non-formulary
  • UCLH:
  • WH:
    • Non-formulary
 
Link  NHSE 170061P: Susoctocog alfa for treating bleeding episodes in people with acquired haemophilia A (all ages)
Factor X (Coagadex)
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Restricted Drug Restricted
High Cost Medicine
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Provider notes

  • NMUH:
    • Non-formulary
  • RFL:
    • Available from the haemphilia centre
  • RNOH:
    • Non-formulary
  • UCLH:
  • WH:
    • Non-formulary
 
Factor XIII Fraction, Dried
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High Cost Medicine
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Provider notes

  • NMUH:
    • Non-formulary
  • RFL:
    • Available from the haemophilia centre
  • RNOH:
    • Non-formulary
  • UCLH:
    • Non-formulary
  • WH:
    • Non-formulary
 
Human fibrinogen
(Riastap)
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Restricted Drug Restricted
High Cost Medicine
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Provider notes

  • NMUH:
    • Non-formulary
  • RFL:
    • Available through the haemophilia centre
  • RNOH:
    • Non-formulary
  • UCLH:
  • WH:
    • Non-formulary
 
Prothrombin Complex Concentrate
(Octaplex)
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Restricted Drug Restricted
High Cost Medicine
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Provider notes

  • NMUH:
    • PbR (Payment by Results) excluded drug. For rapid reversal of anticoagulation in life-threatening bleeding due to oral anticoagulation. To be administered with 5mg of intravenous vitamin K.
  • RFL:
    • Available from the haemophilia centre.
  • RNOH:
    • Non-formulary
  • UCLH:
  • WH:
    • Non-formulary
 
von Willebrand factor
(Willfact)
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Restricted Drug Restricted
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Provider notes

  • NMUH:
    • Non-formulary
  • RFL:
    • Available from the haemophilia centre
  • RNOH:
    • Non-formulary
  • UCLH:
  • WH:
    • Non-formulary
 
Factor XI (Hemoleven)
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Restricted Drug Restricted
High Cost Medicine
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Provider notes

  • NMUH:
    • Non-formulary
  • RFL:
    • Available from the Haemphilia centre
  • RNOH:
    • Non-formulary
  • UCLH:
  • WH:
    • Non-formulary
 
 ....
 Non Formulary Items
Drotrecogin alfa
(Xigris)

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Non Formulary
Protein C Concentrate
(Ceprotin)

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Non Formulary
High Cost Medicine
  
Key
note Notes
Section Title Section Title (top level)
Section Title Section Title (sub level)
First Choice Item First Choice item
Non Formulary Item Non Formulary section
Restricted Drug
Restricted Drug
Unlicensed Drug
Unlicensed
Track Changes
Display tracking information
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Link to adult BNF
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Link to children's BNF
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Link to SPCs
Homecare
Homecare

Traffic Light Status Information

Status Description

GP - Amber

Medicines that should be initiated by a specialist. Prescribing can be transferred to primary care once the patient has been stabilised.

Shared care: For drugs with regular, ongoing need for monitoring and/or assessment of efficacy or toxicity. Prior agreement must be obtained by the specialist from the primary care provider before prescribing responsibility is transferred. The shared care protocol must have been agreed by the relevant secondary care trust Drugs and Therapeutics Committee(s) (DTC) and approved by the North Central London JFC.

Fact sheet: For drugs with some concerns surrounding safety or efficacy but do not require regular monitoring and/or monitoring of effectiveness/toxicity.

  

GP - Red

Medicines which should normally be prescribed by specialists only (hospital only).

For patients already receiving prescriptions in primary care - continue. No new patients to receive prescriptions in primary care.

See link for the complete NCL Red List https://www.ncl-mon.nhs.uk/wp-content/uploads/2017/08/ncl_red_list.pdf

  

Black

Medicines not recommended for routine use in primary or secondary care.

Medicines, which the North Central London JFC has actively reviewed and does not recommend for use at present due to limited clinical and/or cost effective data.

  

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